智鼠故事 
C57BL/6JCya-Cdkn2aem1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Cdkn2aem1flox/Cya
品系编号
CKOCMP-12578-Cdkn2a-B6J-VA
产品编号
S-CKO-01681
基因名
Cdkn2a
小鼠表型
基因别称
Arf，p16，MTS1，Pctr1，p19ARF，p16INK4a，p19，ARF-INK4a，INK4a-ARF，Ink4a/Arf，p16(INK4a)
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Cdkn2a位于小鼠的4号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Cdkn2a基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Melanoma, Cutaneous Malignant 2
Melanoma-Pancreatic Cancer Syndrome
Melanoma-Astrocytoma Syndrome
Lip and Oral Cavity Cancer
Dysplastic Nevus Syndrome
Melanoma
Melanoma, Cutaneous Malignant 1
Bladder Cancer
Precursor T-Cell Acute Lymphoblastic Leukemia
Adrenal Cortical Carcinoma
Gastric Cancer
Ovarian Cancer
Neuroblastoma
Lipoprotein Quantitative Trait Locus
Pancreatic Adenocarcinoma
Li-Fraumeni Syndrome
Skin Melanoma
Skin Squamous Cell Carcinoma
B-Lymphoblastic Leukemia/lymphoma with T(9;22)(q34.1;q11.2)
Bladder Urothelial Carcinoma
Gastric Adenocarcinoma
Suppression of Tumorigenicity 12
Pancreatic Cancer
Renal Cell Carcinoma, Papillary, 1
Lung Squamous Cell Carcinoma
Lung Cancer
Esophageal Cancer
Squamous Cell Carcinoma, Head and Neck
Lung Cancer Susceptibility 3
Hepatocellular Carcinoma
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
