智鼠故事 
C57BL/6JCya-Cntfem1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Cntfem1flox/Cya
品系编号
CKOCMP-12803-Cntf-B6J-VA
产品编号
S-CKO-01792
基因名
Cntf
小鼠表型
基因别称
--
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Cntf位于小鼠的19号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Cntf基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Motor Neuron Disease
Diabetic Neuropathy
Huntington Disease
Autoimmune Optic Neuritis
Nonarteritic Anterior Ischemic Optic Neuropathy
Retinal Degeneration
Embryonal Carcinoma
Lumbosacral Plexus Lesion
Optic Neuritis
Amyotrophic Lateral Sclerosis 1
Neuritis
Central Nervous System Disease
Cold-Induced Sweating Syndrome
Polyneuropathy
Multiple Sclerosis
Crisponi/cold-Induced Sweating Syndrome 2
Intraocular Pressure Quantitative Trait Locus
Sensory Peripheral Neuropathy
Macular Degeneration, Age-Related, 1
Arthrogryposis, Distal, Type 1a
Retinitis Pigmentosa
Retinal Ischemia
Spondylometaphyseal Dysplasia with Corneal Dystrophy
Ischemic Neuropathy
Demyelinating Disease
Spinal Muscular Atrophy
Anemia of Prematurity
Charcot-Marie-Tooth Disease
Eye Degenerative Disease
Strabismus
Punctate Epithelial Keratoconjunctivitis
Diabetic Polyneuropathy
Degeneration of Macula and Posterior Pole
Common Peroneal Nerve Lesion
Glaucoma, Normal Tension
Febrile Seizures, Familial, 1
Telangiectasis
Achromatopsia
Optic Nerve Disease
Parkinson Disease, Late-Onset
Cranial Nerve Disease
Schizophrenia
Glaucoma, Primary Open Angle
Psychotic Disorder
Body Mass Index Quantitative Trait Locus 11
Stargardt Disease
Blood Group, Globoside System
Alzheimer Disease, Familial, 1
Stroke, Ischemic
Eye Disease
Peripheral Nervous System Disease
Leber Plus Disease
Leber Hereditary Optic Neuropathy, Modifier of
Fundus Dystrophy
Nervous System Disease
Type 2 Diabetes Mellitus
Cone-Rod Dystrophy 2
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
