智鼠故事 
C57BL/6JCya-Nf1em1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Nf1em1flox/Cya
品系编号
CKOCMP-18015-Nf1-B6J-VA
产品编号
S-CKO-03928
基因名
Nf1
小鼠表型
基因别称
Dsk9，Nf-1，Mhdadsk9，E030030H24Rik
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Nf1位于小鼠的11号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Nf1基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Neurofibromatosis-Noonan Syndrome
Neurofibromatosis, Type I
Neurofibromatosis, Familial Spinal
Juvenile Myelomonocytic Leukemia
Watson Syndrome
Neurofibromatosis
Neurofibroma
Pilocytic Astrocytoma
Cafe-Au-Lait Spots, Multiple
Optic Nerve Glioma
Pleomorphic Rhabdomyosarcoma
Rhabdomyosarcoma
Inguinal Hernia
Embryonal Rhabdomyosarcoma
Ewing Sarcoma
Skin Disease
Rhabdomyosarcoma 2
Specific Learning Disability
Pheochromocytoma
Hereditary Paraganglioma-Pheochromocytoma Syndromes
Bladder Cancer
Gastric Cancer
Plexiform Neurofibroma
Chromosome 17q11.2 Deletion Syndrome
Ganglioglioma
Chromosome 17q11.2 Duplication Syndrome, 1.4-Mb
Atypical Coarctation of Aorta
Rasopathy
Leukemia, Acute Lymphoblastic 3
Autism Spectrum Disorder
Plasma Cell Neoplasm
Hereditary Breast Ovarian Cancer Syndrome
Myeloma, Multiple
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
