智鼠故事 
C57BL/6JCya-Nppcem1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Nppcem1flox/Cya
品系编号
CKOCMP-18159-Nppc-B6J-VB
产品编号
S-CKO-18351
基因名
Nppc
小鼠表型
基因别称
CNP，lbab
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Nppc位于小鼠的1号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Nppc基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Achondroplasia
Acromesomelic Dysplasia 1
Congestive Heart Failure
Acromesomelic Dysplasia
Camptodactyly-Tall Stature-Scoliosis-Hearing Loss Syndrome
Osteochondrodysplasia
Chagas Disease
Isolated Growth Hormone Deficiency, Type Ia
Hypochondroplasia
Heart Disease
Thanatophoric Dysplasia, Type I
Achondroplasia, Severe, with Developmental Delay and Acanthosis Nigricans
Chronic Kidney Disease
Paraphimosis
Budd-Chiari Syndrome
Kidney Disease
Cardiovascular System Disease
Acrocapitofemoral Dysplasia
Bone Development Disease
Myocardial Infarction
Leri-Weill Dyschondrosteosis
Cystic Fibrosis
Crouzon Syndrome
Lipoprotein Quantitative Trait Locus
Hypertension, Essential
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
