智鼠故事 
C57BL/6JCya-Admem1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Admem1/Cya
品系编号
KOCMP-11535-Adm-B6J-VA
产品编号
S-KO-19100
基因名
Adm
小鼠表型
基因别称
AM
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Adm位于小鼠的7号染色体，采用CRISPR/Cas技术，设计sgRNA，通过应用高通量电转受精卵方式，获得Adm基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Pheochromocytoma
Malignant Hypertension
Pulmonary Hypertension
Congestive Heart Failure
Renal Hypertension
Heart Disease
Ganglioneuroblastoma
Renovascular Hypertension
Vitreoretinopathy, Neovascular Inflammatory
Kidney Disease
Hypertension, Essential
Acute Myocardial Infarction
Kawasaki Disease
Liver Cirrhosis
Oligohydramnios
Ischemia
Pre-Eclampsia
Pyelonephritis
Diabetic Angiopathy
Pneumonia
Neurofibroma
Intracranial Berry Aneurysm
Adrenal Adenoma
Myocardial Infarction
Cardiovascular System Disease
Lung Disease
Macular Holes
Conn's Syndrome
Microvascular Complications of Diabetes 1
Disseminated Chorioretinitis
Tetralogy of Fallot
Systolic Heart Failure
Adrenal Cortical Carcinoma
Type 2 Diabetes Mellitus
Endocrine Organ Benign Neoplasm
Cerebrovascular Disease
Chronic Kidney Disease
Endometrial Cancer
Lipoprotein Quantitative Trait Locus
Diabetes Mellitus
Schizophrenia
Migraine with or Without Aura 1
Stroke, Ischemic
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
在研小鼠
环境标准
SPF
供应地区
全球范围
品系详情
