智鼠故事 
C57BL/6JCya-Csf2em1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Csf2em1flox/Cya
品系编号
CKOCMP-12981-Csf2-B6J-VB
产品编号
S-CKO-01905
基因名
Csf2
小鼠表型
基因别称
CSF，Csfgm，GMCSF，Gm-CSf，MGI-IGM
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Csf2位于小鼠的11号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Csf2基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Pulmonary Alveolar Proteinosis
Mucositis
Cyclic Neutropenia
Leukemia
Neutropenia
Mucormycosis
Stomatitis
Felty Syndrome
Juvenile Myelomonocytic Leukemia
Smallpox
Myeloid Leukemia
Eosinophilic Gastroenteritis
Hypereosinophilic Syndrome
Capillary Leak Syndrome
Diphtheria
Vaccinia
Chronic Granulomatous Disease
Eosinophilic Pneumonia
Aplastic Anemia
Thrombocytosis
Chronic Myelomonocytic Leukemia
Pancytopenia
Pulmonary Eosinophilia
Hypersplenism
Cheilitis
Severe Congenital Neutropenia
Langerhans Cell Histiocytosis
Cytomegalovirus Retinitis
Allergic Disease
Erythema Nodosum
Acquired Immunodeficiency Syndrome
Meconium Aspiration Syndrome
Ileitis
Hyper Ige Syndrome
Onchocerciasis
Dyskeratosis Congenita
Erythroleukemia
Granulocytopenia
Pharyngitis
Acute Leukemia
Myelodysplastic Syndrome
Carotid Artery Thrombosis
T-Cell Large Granular Lymphocyte Leukemia
Allergic Rhinitis
Aspergillosis
Gastroenteritis
Paroxysmal Nocturnal Hemoglobinuria
Arthritis
Lung Disease
Hematologic Cancer
Chorioamnionitis
Thrombocytopenia
Chlamydia
Asthma
Bronchiolitis
Follicular Lymphoma
Leukemia, Chronic Myeloid
Histiocytosis
Hairy Cell Leukemia
Meningitis
Acute Megakaryocytic Leukemia
Combined Immunodeficiency
Polycythemia Vera
Interstitial Lung Disease
Bacterial Infectious Disease
Ileus
Fungal Meningitis
Lymphoma, Non-Hodgkin, Familial
Mastitis
Melanoma
Neutropenia, Severe Congenital, 3, Autosomal Recessive
Rhinitis
Neutrophilia, Hereditary
Palladium Allergic Contact Dermatitis
Cryptococcal Meningitis
Lymphoma, Hodgkin, Classic
Pneumonia
Human Immunodeficiency Virus Infectious Disease
Immune Deficiency Disease
Malaria
Arteriosclerosis
Opportunistic Bacterial Infectious Disease
Nocardiosis
Rheumatoid Arthritis
Temporal Arteritis
Spastic Paraplegia 32, Autosomal Recessive
Lung Cancer
Severe Combined Immunodeficiency
Dermatitis
Myeloproliferative Neoplasm
Myelodysplastic/myeloproliferative Neoplasm
Leukocyte Disease
Fungal Infectious Disease
Chronic Asthma
Primary Bacterial Infectious Disease
Opportunistic Mycosis
Chronic Eosinophilic Pneumonia
Bronchial Disease
Dermatitis, Atopic
Deficiency Anemia
Respiratory Allergy
Leukemia, Acute Lymphoblastic
Lymphoid Interstitial Pneumonia
Renal Cell Carcinoma, Nonpapillary
Colorectal Cancer
Autoimmune Myocarditis
Severe Covid-19
Nose Disease
Central Nervous System Vasculitis
Bacterial Sepsis
Nasal Cavity Disease
Acute Promyelocytic Leukemia
Senile Entropion
Cryptococcosis
Critical Covid-19
Acute Asthma
Primary Systemic Mycosis
Pulmonary Fibrosis
Coronavirus Infectious Disease
Bacterial Pneumonia
Autoimmune Disease of Central Nervous System
Ovarian Cancer
Cellulitis
Integumentary System Disease
Systemic Lupus Erythematosus
Parasitic Helminthiasis Infectious Disease
Autoimmune Disease of Musculoskeletal System
Autoimmune Disease of Skin and Connective Tissue
Myeloma, Multiple
Crohn's Disease
Multiple Sclerosis
Autoimmune Disease of Cardiovascular System
Bone Inflammation Disease
Bladder Cancer
Contact Dermatitis
Exanthem
Leukemia, Chronic Lymphocytic
Neutrophilic Dermatosis, Acute Febrile
Splenic Disease
Blood Platelet Disease
Blood Coagulation Disease
Commensal Bacterial Infectious Disease
Parasitic Protozoa Infectious Disease
Hemophagocytic Lymphohistiocytosis
Demyelinating Disease
Bone Marrow Cancer
Visceral Leishmaniasis
Chronic Mucocutaneous Candidiasis
Myeloid and Lymphoid Neoplasms Associated with Pdgfra Rearrangement
Squamous Cell Carcinoma, Head and Neck
Prostate Cancer
Respiratory Failure
Leprosy 3
Granulomatosis with Polyangiitis
Diabetes Mellitus
Macs Syndrome
Autism Spectrum Disorder
Gliosarcoma
Skin Disease
Leukemia, Acute Myeloid
Behcet Syndrome
Connective Tissue Disease
Breast Adenocarcinoma
Peripheral Nervous System Disease
Interstitial Lung Disease 2
Blood Group, Globoside System
Celiac Disease 1
Nervous System Disease
Wilms Tumor 1
Eye Disease
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
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