智鼠故事 
C57BL/6JCya-Pou5f1em1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Pou5f1em1flox/Cya
品系编号
CKOCMP-18999-Pou5f1-B6J-VA
产品编号
S-CKO-04393
基因名
Pou5f1
小鼠表型
基因别称
Oct3，Oct4，Otf3，Otf4，NF-A3，Oct-3，Oct-4，Otf-3，Otf-4，Otf3g，Oct3/4，Oct-3/4，Otf3-rs7
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Pou5f1位于小鼠的17号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Pou5f1基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Embryonal Carcinoma
Teratoma
Germinoma
Seminoma
Germ Cell and Embryonal Cancer
Teratocarcinoma
Pineoblastoma
Ocular Cancer
Tyrosinemia
Sarcoma
Ovarian Embryonal Carcinoma
Gonadal Dysgenesis
Malignant Teratoma
Mature Teratoma
Germ Cell Cancer
Mixed Germ Cell Cancer
Brain Germinoma
Ovarian Primitive Germ Cell Tumor
Hard Palate Cancer
Ovarian Endodermal Sinus Tumor
Spermatogenic Failure, Y-Linked, 1
Hepatocellular Carcinoma
Endodermal Sinus Tumor
Adhesions of Uterus
Testicular Disease
Intratubular Embryonal Carcinoma
Dysgerminoma of Ovary
Childhood Testicular Germ Cell Tumor
Testicular Germ Cell Cancer
Medulloblastoma
Macular Degeneration, Age-Related, 7
Ewing Sarcoma
Spermatocytoma
Diencephalic Astrocytoma
Neuroblastoma
Glioblastoma Classical Subtype
Gastric Cancer
Ovarian Cancer
Testicular Cancer
Prostate Cancer
Colorectal Cancer
Premature Menopause
Parkinson Disease 17
Parkinson Disease, Late-Onset
Severe Combined Immunodeficiency
Cryptorchidism, Unilateral or Bilateral
Wilms Tumor 1
Leukemia, Acute Myeloid
Peripheral Nervous System Disease
Nervous System Disease
Eye Disease
Amyotrophic Lateral Sclerosis 1
Retinitis Pigmentosa
Microcephaly
Congenital Nervous System Abnormality
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
在研小鼠
环境标准
SPF
供应地区
全球范围
