智鼠故事 
C57BL/6JCya-Rps27aem1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Rps27aem1flox/Cya
品系编号
CKOCMP-78294-Rps27a-B6J-VA
产品编号
S-CKO-16792
基因名
Rps27a
小鼠表型
基因别称
Ubb，Ubc，Uba52，0610006J14Rik
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Rps27a位于小鼠的11号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Rps27a基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Machado-Joseph Disease
Neuronal Intranuclear Inclusion Disease
Pick Disease of Brain
Motor Neuron Disease
Inclusion Body Myositis
Influenza
Tauopathy
Frontotemporal Lobar Degeneration with Tdp43 Inclusions, Grn-Related
Frontotemporal Dementia
Amyloidosis
Parkinsonism
Semantic Dementia
Paget's Disease of Bone
Dementia
Myopathy, Myofibrillar, 1
Angelman Syndrome
Creutzfeldt-Jakob Disease
Diamond-Blackfan Anemia
Dementia, Lewy Body
Rem Sleep Behavior Disorder
Supranuclear Palsy, Progressive, 1
Neurodegeneration with Brain Iron Accumulation 2a
Multiple System Atrophy 1
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes
Amyotrophic Lateral Sclerosis 1
Striatonigral Degeneration
Parkinson Disease, Late-Onset
Myopathy
Autosomal Dominant Cerebellar Ataxia
Huntington Disease
Alzheimer Disease, Familial, 1
Alexander Disease
Movement Disease
Gastrointestinal Stromal Tumor
Acute Promyelocytic Leukemia
Colorectal Cancer
Type 2 Diabetes Mellitus
Fanconi Anemia, Complementation Group a
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
在研小鼠
环境标准
SPF
供应地区
全球范围
