智鼠故事 
C57BL/6JCya-Il1aem1flox/Cya 条件性基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Il1aem1flox/Cya
品系编号
CKOCMP-16175-Il1a-B6J-VB
产品编号
S-CKO-19285
基因名
Il1a
小鼠表型
基因别称
Il-1a
品系背景
C57BL/6JCya
修饰方式
条件性基因敲除
品系描述
Il1a位于小鼠的2号染色体，采用基因编辑技术，通过高通量电转受精卵方式，获得Il1a基因条件性敲除小鼠，性成熟后取精子冻存。
相关疾病：
Cholesteatoma of Middle Ear
Keratoconjunctivitis Sicca
Arthritis
Silicosis
Gingivitis
Contact Dermatitis
Bacterial Vaginosis
Bullous Keratopathy
Tonsillitis
Dysentery
Pars Planitis
Leishmaniasis
Hantavirus Pulmonary Syndrome
Aggressive Periodontitis
Rheumatoid Arthritis
Alopecia Areata
Acne
Periodontitis
Erythema Nodosum
Hidradenitis Suppurativa
Schistosomiasis
Hidradenitis
Laryngitis
Typhoid Fever
Pneumoconiosis
Root Resorption
Shigellosis
Cryptosporidiosis
Pertussis
Trypanosomiasis
Interstitial Lung Disease
Uveitis
Proteasome-Associated Autoinflammatory Syndrome 1
Gingival Overgrowth
Psoriatic Arthritis
Osteomyelitis
Synovitis
Paratyphoid Fever
Thrombocytosis
Chorioamnionitis
Corneal Disease
Osteoarthritis
Cholesteatoma of External Ear
Hairy Cell Leukemia
Liver Disease
Leptospirosis
Malaria
Cutaneous Leishmaniasis
Polymyositis
Keratoconjunctivitis
Pyelonephritis
Osteoporosis
Venous Insufficiency
Spondylitis
Inflammatory Bowel Disease
Ileus
Alcoholic Liver Cirrhosis
Kawasaki Disease
Influenza
Endocarditis
Graves' Disease
Dermatitis
Dermatomyositis
Sudden Infant Death Syndrome
Indolent Plasma Cell Myeloma
Chlamydia
Prostatitis
Pemphigus Foliaceus
Pemphigoid
Aspergillosis
Lichen Planus
Irritable Bowel Syndrome
Schnitzler Syndrome
Connective Tissue Disease
Meningitis
Sebaceous Gland Disease
Toxic Shock Syndrome
Tetanus
Gingival Disease
Temporal Arteritis
Pemphigus
Juvenile Rheumatoid Arthritis
Cystitis
Psoriasis
Autoimmune Disease
Bronchiolitis
Extrinsic Allergic Alveolitis
Myocarditis
Mumps
Stomatitis
Muscular Dystrophy
Myasthenia Gravis
Fibrosarcoma
Periodic Fever, Familial, Autosomal Dominant
Alopecia
Adult-Onset Still's Disease
Cinca Syndrome
Sarcoidosis 1
Endometriosis
Pneumonia
Vaginal Disease
Bone Inflammation Disease
Lung Disease
Cholera
Pemphigus Vulgaris, Familial
Autoimmune Disease of Musculoskeletal System
Bacterial Sepsis
Autoimmune Disease of Skin and Connective Tissue
Keratoconus
Pulpitis
Papilloma
Periapical Periodontitis
Craniopharyngioma
Mevalonic Aciduria
Sapho Syndrome
Idiopathic Inflammatory Myopathy
Aplastic Anemia
Coronary Aneurysm
Bacterial Infectious Disease
Central Nervous System Vasculitis
Thrombocytopenia
Pulmonary Fibrosis
Autoimmune Disease of Cardiovascular System
Neutrophilic Dermatosis, Acute Febrile
Neutropenia
Chronic Recurrent Multifocal Osteomyelitis
Skin Disease
Heart Aneurysm
Pericardium Disease
Lacrimal Apparatus Disease
Lymphoid Interstitial Pneumonia
Conjunctival Disease
Pericoronitis
Vaginitis
Serum Amyloid a Amyloidosis
Miliaria
Narcolepsy
Pustulosis of Palm and Sole
Immune Deficiency Disease
Familial Cold Autoinflammatory Syndrome
Scleral Disease
Muckle-Wells Syndrome
Coronavirus Infectious Disease
Integumentary System Disease
Severe Covid-19
Chronic Atticoantral Disease
Periostitis
Heart Disease
Decubitus Ulcer
Septic Arthritis
Dry Eye Syndrome
Periodontitis, Aggressive, 1
Spondyloarthropathy
Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, and Acne
Interstitial Lung Disease 2
Aortitis
Primary Bacterial Infectious Disease
Tooth Resorption
Systemic Lupus Erythematosus
Alcohol Dependence
Anterior Uveitis
Mooren's Ulcer
Lymph Node Disease
Ovarian Cancer
Viral Pneumonia
Exanthem
Critical Covid-19
Spinal Disease
Pre-Eclampsia
Crohn's Disease
Panuveitis
Autoimmune Myocarditis
Aphthous Stomatitis
Commensal Bacterial Infectious Disease
Lipoprotein Quantitative Trait Locus
Chronic Conjunctivitis
Extrinsic Cardiomyopathy
Bronchial Disease
Seborrheic Dermatitis
Beta-Thalassemia
Fungal Infectious Disease
Epididymis Disease
Chorioretinitis
Chondromalacia
Colorectal Cancer
Endometrial Disease
Dental Pulp Disease
Bacterial Pneumonia
Chronic Ulcer of Skin
Dermatitis, Atopic
Opportunistic Mycosis
Allergic Conjunctivitis
Spondyloarthropathy 1
Autoimmune Disease of Gastrointestinal Tract
Hemophagocytic Lymphohistiocytosis
Parasitic Protozoa Infectious Disease
Tendinitis
Uveal Disease
Bursitis
Anthracosis
Multiple Sclerosis
Autoimmune Disease of Central Nervous System
Vaginal Discharge
Hypersensitivity Reaction Type Iv Disease
Blepharitis
Asthma
Allergic Contact Dermatitis
Localized Scleroderma
Long Covid
Chronic Fatigue Syndrome
Aseptic Meningitis
Autoimmune Disease of Exocrine System
Bronchopneumonia
Cellulitis
Preterm Premature Rupture of the Membranes
Nose Disease
Anaerobic Pneumonia
Sweat Gland Disease
Myocardial Infarction
Parasitic Helminthiasis Infectious Disease
Leukocyte Disease
Urinary Tract Infection
Systemic Scleroderma
Keratitis, Hereditary
Pancreatic Cancer
Coccidiosis
Leprosy 3
Middle Ear Disease
Lung Cancer
Autoimmune Disease of Endocrine System
Diabetes Mellitus
Blood Coagulation Disease
Behcet Syndrome
Bladder Cancer
Null-Cell Leukemia
Salmonellosis
Demyelinating Disease
Respiratory Failure
Bone Resorption Disease
Hypertension, Essential
Alzheimer Disease, Familial, 1
Gastric Cancer
Macular Degeneration, Age-Related, 1
Immune System Disease
Takayasu Arteritis
Blood Platelet Disease
T-Cell Acute Lymphoblastic Leukemia
Prostate Cancer
Schizophrenia
Gastroesophageal Reflux
Blood Group, Globoside System
Celiac Disease 1
Myelodysplastic Syndrome
Intracranial Berry Aneurysm
Breast Adenocarcinoma
Eye Disease
Peripheral Nervous System Disease
Diamond-Blackfan Anemia 1
Macs Syndrome
Nervous System Disease
Migraine with or Without Aura 1
Deficiency Anemia
Body Mass Index Quantitative Trait Locus 11
Type 2 Diabetes Mellitus
Amyotrophic Lateral Sclerosis 1
Dilated Cardiomyopathy
Leukemia, Acute Myeloid
Retinitis Pigmentosa
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
在研小鼠
环境标准
SPF
供应地区
全球范围
