智鼠故事 
C57BL/6JCya-Grm5em1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Grm5em1/Cya
品系编号
KOCMP-108071-Grm5-B6J-VA
产品编号
S-KO-00570
基因名
Grm5
小鼠表型
基因别称
Glu5R，Gprc1e，mGluR5，mGluR5b，6430542K11Rik
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Grm5位于小鼠的7号染色体，采用基因编辑技术，通过应用高通量电转受精卵方式，获得Grm5基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Fragile X Syndrome
Central Nervous System Disease
Temporal Lobe Epilepsy
Status Epilepticus
Obsessive-Compulsive Disorder
Granulomatous Angiitis
Tuberous Sclerosis
Attention Deficit-Hyperactivity Disorder
Epilepsy
Depressive Disorder
Focal Epilepsy
Schizophrenia
Schizophrenia 6
Alcohol Dependence
Anterograde Amnesia
Autism Spectrum Disorder
X-Linked Hereditary Ataxia
Parkinson Disease, Late-Onset
Autism
Pervasive Developmental Disorder
Fragile X-Associated Tremor/ataxia Syndrome
Phelan-Mcdermid Syndrome
Specific Developmental Disorder
Substance Dependence
Gallbladder Small Cell Carcinoma
Psychotic Disorder
Premature Ovarian Failure 1
Substance Abuse
Disease of Mental Health
Gastroesophageal Reflux
Migraine with or Without Aura 1
Childhood Absence Epilepsy
Amyotrophic Lateral Sclerosis 1
Nervous System Disease
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
