智鼠故事 
C57BL/6JCya-Hspa4em1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Hspa4em1/Cya
品系编号
KOCMP-15525-Hspa4-B6J-VA
产品编号
S-KO-02529
基因名
Hspa4
小鼠表型
基因别称
70kDa，APG-2，Hsp110，Hsp70RY，mKIAA4025
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Hspa4位于小鼠的11号染色体，采用基因编辑技术，通过应用高通量电转受精卵方式，获得Hspa4基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Babesiosis
Vulvovaginitis
Transient Cerebral Ischemia
Chronic Cervicitis
Oculopharyngeal Muscular Dystrophy 1
Arthritis
Ulcerative Colitis
Leishmaniasis
Ischemia
Auditory System Disease
Spinocerebellar Ataxia, Autosomal Recessive 18
Spinocerebellar Ataxia 7
Colitis
Huntington Disease
Diabetes Mellitus
Malaria
Erythroleukemia
Mucocutaneous Leishmaniasis
Meniere Disease
Rheumatoid Arthritis
Rabies
Coenurosis
Viral Hepatitis
Nasopharyngeal Carcinoma
Dementia
Stroke, Ischemic
Spinal and Bulbar Muscular Atrophy, X-Linked 1
Arrhythmogenic Right Ventricular Cardiomyopathy
Colorectal Cancer
Parasitic Protozoa Infectious Disease
Vascular Disease
Cogan Syndrome
Cryptosporidiosis
Cutaneous Leishmaniasis
Lung Cancer
Hepatocellular Carcinoma
Splenic Disease
Epilepsy
Visceral Leishmaniasis
Coccidiosis
Sensorineural Hearing Loss
Cystic Fibrosis
Prostate Cancer
Leukemia, Chronic Myeloid
Prion Disease
Microcephaly 7, Primary, Autosomal Recessive
Neuroblastoma
Bladder Cancer
Sarcoidosis 1
Ovarian Cancer
Endometrial Cancer
Asthma
Motor Neuron Disease
Parkinson Disease, Late-Onset
American Histoplasmosis
Retinitis Pigmentosa 61
Vaginal Adenoma
Gastric Cancer
Skin Disease
Heterophyiasis
Lymphoma, Non-Hodgkin, Familial
Autosomal Dominant Cerebellar Ataxia
Hereditary Ataxia
Myofibrillar Myopathy
Machado-Joseph Disease
Cerebellar Disease
Frontotemporal Dementia
Hypertension, Essential
Amyotrophic Lateral Sclerosis 1
Peripheral Nervous System Disease
Spastic Ataxia
Nervous System Disease
Type 2 Diabetes Mellitus
Eye Disease
Alzheimer Disease, Familial, 1
Dilated Cardiomyopathy
Leukemia, Acute Myeloid
Retinitis Pigmentosa
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
