智鼠故事 
C57BL/6JCya-Il4em1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Il4em1/Cya
品系编号
KOCMP-16189-Il4-B6J-VA
产品编号
S-KO-02648
基因名
Il4
小鼠表型
基因别称
Il-4，BSF-1
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Il4位于小鼠的11号染色体，采用基因编辑技术，通过应用高通量电转受精卵方式，获得Il4基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Schistosomiasis
Allergic Rhinitis
Allergic Disease
Food Allergy
Allergic Asthma
Allergic Bronchopulmonary Aspergillosis
Intrinsic Asthma
Conjunctival Disease
Pulmonary Eosinophilia
Acute Lung Injury
Allergic Conjunctivitis
Dermatitis
Cutaneous Leishmaniasis
Colitis
Vernal Conjunctivitis
Tetanus
Leishmaniasis
Pulmonary Tuberculosis
Giant Papillary Conjunctivitis
Hyper Ige Syndrome
Egg Allergy
Vulvovaginal Candidiasis
Ulcerative Colitis
Visceral Leishmaniasis
Opisthorchiasis
Rhinitis
Severe Covid-19
Folliculitis
Penicillin Allergy
Keratoconjunctivitis
Conjunctivitis
Smallpox
Vernal Keratoconjunctivitis
Eosinophilic Gastroenteritis
Keratoconjunctivitis Sicca
Trichinosis
Onchocerciasis
Asthma
Endomyocardial Fibrosis
Allergic Contact Dermatitis
Dermatitis, Atopic
Mikulicz Disease
Respiratory Allergy
Uveitis
Myasthenia Gravis
Chronic Asthma
Trypanosomiasis
Papilloma
Childhood-Onset Asthma
Graves' Disease
Nasal Cavity Disease
Nose Disease
Inflammatory Bowel Disease
Autoimmune Disease
Brucellosis
Trachoma
Severe Combined Immunodeficiency, X-Linked
Immune Thrombocytopenia
Paracoccidioidomycosis
Pemphigoid
Scleritis
Common Variable Immunodeficiency
Covid-19
Subacute Sclerosing Panencephalitis
Toxoplasmosis
Eosinophilic Pneumonia
Immunodeficiency with Hyper-Igm, Type 1
1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis
Bronchiolitis
Lepromatous Leprosy
Dermatitis Herpetiformis
Immune Deficiency Disease
Acute Asthma
Milk Allergy
Skin Disease
Aggressive Periodontitis
Parasitic Helminthiasis Infectious Disease
Leptospirosis
Burkitt Lymphoma
Bronchial Disease
Blepharoconjunctivitis
Adenoid Hypertrophy
Gastroenteritis
Esophagitis
Periodontitis
Hypereosinophilic Syndrome
Toxic Shock Syndrome
Taeniasis
Severe Combined Immunodeficiency
Periapical Granuloma
Aspergillosis
Tonsillitis
Multiple Sclerosis
Rubella
Silicosis
Erythema Multiforme
Alopecia Areata
Mycobacterium Tuberculosis 1
Relapsing-Remitting Multiple Sclerosis
Immunoglobulin a Deficiency 1
Neuritis
Sezary's Disease
Malaria
Urticaria
Rheumatoid Arthritis
Chronic Conjunctivitis
Combined Immunodeficiency
Chlamydia
Blau Syndrome
Rheumatic Heart Disease
Chorioamnionitis
Mastocytosis
Hepatitis a
Gingivitis
Root Resorption
Bronchitis
Lichen Planus
Legume Allergy
Thyroiditis
Diphtheria
Intestinal Schistosomiasis
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Purpura
Irritable Bowel Syndrome
Cystitis
Osteomyelitis
Splenic Disease
Human Immunodeficiency Virus Infectious Disease
Viral Hepatitis
Pemphigus
Viral Infectious Disease
Bullous Pemphigoid
Prostatitis
Psoriasis
Childhood T-Cell Acute Lymphoblastic Leukemia
Papillary Conjunctivitis
Interstitial Lung Disease
Kawasaki Disease
Neuromyelitis Optica
Hashimoto Thyroiditis
Parasitic Protozoa Infectious Disease
Elephantiasis
Central Nervous System Leiomyosarcoma
Paranasal Sinus Disease
Omenn Syndrome
Occupational Asthma
Environmental Induced Asthma
Filarial Elephantiasis
Arthritis
Cholera
Toxocariasis
Peanut Allergy
Meningitis
Systemic Lupus Erythematosus
Igg4-Related Disease
Mucocutaneous Leishmaniasis
Chronic Rhinitis
Intermittent Asthma
Urinary Schistosomiasis
Fruit Allergy
Retinitis Pigmentosa 46
Contact Dermatitis
Integumentary System Disease
T2-High Asthma
Myocarditis
Primary Bacterial Infectious Disease
Pneumonia
Alopecia
Gastritis
Chronic Myelomonocytic Leukemia
Proteasome-Associated Autoinflammatory Syndrome 1
Arteriosclerosis
Coccidiosis
Chronic Spontaneous Urticaria
Stomatitis
T2-Low Asthma
Peritonitis
Parasitic Ectoparasitic Infectious Disease
Persistent Severe Asthma
Kimura Disease
Cough Variant Asthma
Encephalitis
Fungal Infectious Disease
Autoimmune Myocarditis
Metal Allergy
Neurodermatitis
Loiasis
Near-Fatal Asthma
Cystic Echinococcosis
Cow Milk Allergy
Common Cold
Eczema Herpeticum
Tuberculoid Leprosy
Pollen Allergy
Pancreatic Cancer
Leukocyte Disease
Thunderstorm Triggered Asthma
Esophagitis, Eosinophilic, 1
Lymphopenia
Aplastic Anemia
Nocturnal Asthma
Primary Systemic Mycosis
Lymphoid Interstitial Pneumonia
Strongyloidiasis
Commensal Bacterial Infectious Disease
Autoimmune Disease of Skin and Connective Tissue
Glomerulonephritis
Pulmonary Fibrosis
Autoimmune Disease of Musculoskeletal System
Opportunistic Mycosis
Chondroblastoma
Blepharitis
Mycoplasma Pneumoniae Pneumonia
Temporal Arteritis
Autoimmune Disease of Central Nervous System
Alveolar Echinococcosis
Chromium Allergic Contact Dermatitis
Cysticercosis
Autoimmune Disease of Gastrointestinal Tract
Exercise-Induced Bronchoconstriction
Autoimmune Disease of Eyes, Ear, Nose and Throat
Leprosy 3
Localized Scleroderma
Cercarial Dermatitis
Eosinophilic Meningitis
Cerebral Palsy
Crab Allergy
B Cell Deficiency
Autoimmune Uveitis
Lichen Disease
Mite Infestation
Ascaris Lumbricoides Infection
Vasomotor Rhinitis
Neutropenia
Bone Inflammation Disease
Anisakiasis
Crohn's Disease
Heart Disease
Cryptococcosis
Cryptococcal Meningitis
Fungal Meningitis
Drug Allergy
Enterobiasis
Churg-Strauss Syndrome
Pre-Eclampsia
Dacryoadenitis
Autoimmune Disease of Exocrine System
Autoimmune Disease of Cardiovascular System
Nephrotic Syndrome
Scabies
West Nile Encephalitis
Immunodeficiency with Hyper-Igm, Type 2
Autoimmune Disease of Endocrine System
Extrapulmonary Tuberculosis
Herpangina
Leukemia, Chronic Lymphocytic
Filariasis
Colorectal Cancer
Chronic Meningitis
Beta-Lactam Allergy
Laryngitis
Tick Infestation
T Cell Deficiency
Congenital Toxoplasmosis
Immunodysregulation, Polyendocrinopathy, and Enteropathy, X-Linked
Type 1 Diabetes Mellitus
Hypothyroidism
Renal Cell Carcinoma, Nonpapillary
Upper Respiratory Tract Disease
Autoimmune Disease of Blood
Chickenpox
Autoimmune Glomerulonephritis
Thrombocytopenia
Skin Atrophy
Eyelid Disease
Immune System Disease
Alopecia Universalis Congenita
Demyelinating Disease
Extrinsic Cardiomyopathy
Salmonellosis
Coronavirus Infectious Disease
Lacrimal Apparatus Disease
Gingival Disease
Middle Ear Disease
Hypersensitivity Reaction Type Iv Disease
Cystic Fibrosis
Systemic Scleroderma
Vaginal Disease
Uveal Disease
Bacterial Pneumonia
Chronic Fatigue Syndrome
Exanthem
Primary Progressive Multiple Sclerosis
Bullous Skin Disease
Salivary Gland Disease
Pelvic Organ Prolapse
Type 1 Diabetes Mellitus 8
Myeloma, Multiple
Osteoporosis
Lung Cancer
Bladder Cancer
Type 2 Diabetes Mellitus
Immunodeficiency 7
Diabetes Mellitus
Granulomatosis with Polyangiitis
Amebiasis
Spondyloarthropathy
Rectal Disease
Myocardial Infarction
Gastroesophageal Reflux
Gastric Cancer
Epilepsy
Hair Disease
Otitis Media
Potocki-Shaffer Syndrome
Lipoprotein Quantitative Trait Locus
Celiac Disease 1
Sarcoidosis 1
Ovarian Cancer
Prostate Cancer
Behcet Syndrome
Interstitial Lung Disease 2
Chronic Mucocutaneous Candidiasis
Connective Tissue Disease
Schizophrenia
Hypertension, Essential
Diamond-Blackfan Anemia 1
Blood Platelet Disease
Cholangitis, Primary Sclerosing
Primary Biliary Cholangitis
Eye Disease
Macs Syndrome
Breast Adenocarcinoma
Peripheral Nervous System Disease
Nervous System Disease
Body Mass Index Quantitative Trait Locus 11
Leukemia, Acute Myeloid
Amyotrophic Lateral Sclerosis 1
Dilated Cardiomyopathy
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
在研小鼠
环境标准
SPF
供应地区
全球范围
