智鼠故事 
C57BL/6JCya-Timp2em1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Timp2em1/Cya
品系编号
KOCMP-21858-Timp2-B6J-VB
产品编号
S-KO-05440
基因名
Timp2
小鼠表型
基因别称
Timp-2，D11Bwg1104e
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Timp2位于小鼠的11号染色体，采用基因编辑技术，通过应用高通量电转受精卵方式，获得Timp2基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Conjunctivochalasis
Fibrosarcoma
Gingival Hypertrophy
Pulmonary Emphysema
Aortic Aneurysm, Familial Abdominal, 1
Cervical Squamous Cell Carcinoma
Adenocarcinoma
Varicose Veins
Synovitis
Tropical Spastic Paraparesis
Venous Insufficiency
Breast Ductal Carcinoma
Spinal Stenosis
Bacterial Meningitis
Aortic Aneurysm
Sorsby Fundus Dystrophy
Endometrial Cancer
Pancreatic Adenocarcinoma
Chronic Ulcer of Skin
Pneumothorax
Lymphangioleiomyomatosis
Vitreoretinopathy, Neovascular Inflammatory
Corneal Neovascularization
Intraocular Pressure Quantitative Trait Locus
Endometriosis
Lung Cancer
Microvascular Complications of Diabetes 1
Bladder Cancer
Gallbladder Cancer
Breast Fibroadenoma
Ovarian Cancer
Colorectal Cancer
Large Cell Carcinoma
Bronchiolo-Alveolar Adenocarcinoma
Gastric Cancer
Laryngeal Squamous Cell Carcinoma
Myopia
Preterm Premature Rupture of the Membranes
Rheumatoid Arthritis
Anaplastic Astrocytoma
Breast Intraductal Papillomatosis
High Grade Glioma
Heart Disease
Vascular Disease
Hepatocellular Carcinoma
Scoliosis
Prostate Cancer
Squamous Cell Carcinoma, Head and Neck
Inguinal Hernia
Aortic Valve Disease 1
Aortic Aneurysm, Familial Thoracic 1
Renal Cell Carcinoma, Nonpapillary
Moyamoya Disease 1
Fundus Dystrophy
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
在研小鼠
环境标准
SPF
供应地区
全球范围
