智鼠故事 
C57BL/6JCya-Pde5aem1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Pde5aem1/Cya
品系编号
KOCMP-242202-Pde5a-B6J-VA
产品编号
S-KO-07347
基因名
Pde5a
小鼠表型
基因别称
Cn5n，Pde5，Cgbpde，PDE5a2，Pde5a1
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Pde5a位于小鼠的3号染色体，采用基因编辑技术，通过应用高通量电转受精卵方式，获得Pde5a基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Impotence
Priapism
Nonarteritic Anterior Ischemic Optic Neuropathy
Pulmonary Hypertension
Prostatitis
Psychosexual Disorder
Penile Disease
Sexual Health Disorder
Peyronie's Disease
Heart Disease
Vasculogenic Impotence
Raynaud Disease
Prostatic Hyperplasia, Benign
Peyronie Disease
Hypogonadism
Bladder Neck Obstruction
Urethral Syndrome
Ureterolithiasis
Chronic Pulmonary Heart Disease
Inhibited Female Orgasm
Hypoactive Sexual Desire Disorder
Optic Nerve Disease
Premature Ejaculation
Congestive Heart Failure
Diastolic Heart Failure
Pulmonary Venoocclusive Disease
Hepatic Encephalopathy
Prostatic Hypertrophy
Cardiovascular System Disease
Persistent Fetal Circulation Syndrome
Ischemia
Low Compliance Bladder
Tricuspid Valve Insufficiency
Tricuspid Valve Disease
Pulmonary Valve Insufficiency
Transient Global Amnesia
Retinitis Pigmentosa 72
Lipoprotein Quantitative Trait Locus
Urethral Stricture
Myocardial Infarction
Retinitis Pigmentosa 46
Diabetes Mellitus
Articulation Disorder
Systolic Heart Failure
Lipid Metabolism Disorder
Pre-Eclampsia
Peripheral Vascular Disease
Ocular Hyperemia
Diaphragm Disease
Orthostatic Hypotension
Vascular Disease
Hypertension, Essential
Phimosis
Stuttering
Retinitis Pigmentosa 90
Atrial Septal Defect 8
Pulmonary Disease, Chronic Obstructive
Diaphragmatic Hernia, Congenital
Limited Scleroderma
Migraine with or Without Aura 1
Microphthalmia, Isolated 1
Patent Ductus Arteriosus 1
Type 2 Diabetes Mellitus
Patent Foramen Ovale
Body Mass Index Quantitative Trait Locus 11
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
