智鼠故事 
C57BL/6JCya-Iappem1/Cya 基因敲除小鼠
基本信息
品系名称
C57BL/6JCya-Iappem1/Cya
品系编号
KOCMP-15874-Iapp-B6J-VB
产品编号
S-KO-16503
基因名
Iapp
小鼠表型
基因别称
DAP
品系背景
C57BL/6JCya
修饰方式
全身性基因敲除
品系描述
Iapp位于小鼠的6号染色体，采用基因编辑技术，通过应用高通量电转受精卵方式，获得Iapp基因敲除小鼠，性成熟后取精子冻存。
相关疾病：
Insulinoma
Amyloidosis
Islet Cell Tumor
Hyperglycemia
Type 2 Diabetes Mellitus
Prediabetes Syndrome
Hypoglycemia
Type 1 Diabetes Mellitus
Dialysis-Related Amyloidosis
Gestational Diabetes
Diabetes Mellitus
Wild-Type Amyloidosis
Alzheimer Disease 6
Amyloidosis, Hereditary, Transthyretin-Related
Amyloidosis, Familial Visceral
Leptin Deficiency or Dysfunction
Pancreatic Cystadenoma
Hyperinsulinism
Cerebral Amyloid Angiopathy, Cst3-Related
Creutzfeldt-Jakob Disease
Osteoporosis
Body Mass Index Quantitative Trait Locus 11
Alzheimer Disease, Familial, 1
Prion Disease
Abnormality of Glucagon Secretion
Monocarboxylate Transporter 1 Deficiency
Pancreatic Cancer
Maturity-Onset Diabetes of the Young
Hypertension, Essential
Migraine with or Without Aura 1
Parkinson Disease, Late-Onset
Nervous System Disease
质控标准
精子检测
① 冷冻前验证精子活力观察
② 冷冻验证每批次进行复苏验证
品系状态
活体
环境标准
SPF
供应地区
全球范围
