智鼠故事 
Eno2-P2A-CreERT2
复苏/繁育服务
产品名称：
Eno2-P2A-CreERT2
产品编号：
C001578
品系背景：
C57BL/6JCya
表达组织/细胞举例：
神经系统，成熟神经元
* 使用本品系发表的文献需注明：Eno2-P2A-CreERT2 mice (Catalog C001578) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
只
品系描述
Eno2-P2A-CreERT2 小鼠是通过基因编辑技术将 P2A-CreERT2 基因表达组件插入小鼠 Eno2 基因中，在小鼠 Eno2 基因调控元件的驱动下表达 CreERT2 重组酶所构建的。在未经他莫昔芬处理的情况下，CreERT2重组酶主要存在于细胞质中；只有在他莫昔芬的作用下，CreERT2 重组酶才能进入细胞核并发挥其重组作用。当 Eno2-P2A-CreERT2 小鼠与含有 loxP 位点的小鼠杂交后，他莫昔芬诱导后预计在子代小鼠的神经系统（成熟神经元）中引发由 Cre 重组酶介导的 loxP 位点间的序列重组。
相关疾病：
Granular Cell Tumor
Creutzfeldt-Jakob Disease
Olfactory Neuroblastoma
Bronchus Cancer
Neuroendocrine Carcinoma
Hypoxic Ischemic Encephalopathy
Hemangioblastoma
Small Cell Osteogenic Sarcoma
Merkel Cell Carcinoma
Large Cell Carcinoma
Neuroendocrine Tumor
Spondylosis
Carcinoid Tumors, Intestinal
Optic Nerve Glioma
Ganglioglioma
Status Epilepticus
Alveolar Soft Part Sarcoma
Melanotic Neuroectodermal Tumor
Cardiac Arrest
Myoblastoma
Congenital Epulis
Post-Cardiac Arrest Syndrome
Paraganglioma
Neuroma
Gastric Small Cell Carcinoma
Epulis
Ewing Sarcoma
Endometrial Small Cell Carcinoma
Childhood Ovarian Dysgerminoma
Childhood Ovarian Germ Cell Tumor
Teratoma
Olfactory Neural Tumor
Malignant Olfactory Nerve Neoplasm
Esophagus Small Cell Carcinoma
Cauda Equina Neoplasm
Ganglioneuroblastoma
Mesenchymal Chondrosarcoma
Secondary Progressive Multiple Sclerosis
Ganglioneuroma
Subependymal Giant Cell Astrocytoma
Lambert-Eaton Myasthenic Syndrome
Seminoma
Glomus Tumor
Somatostatinoma
Gastrointestinal Stromal Tumor
Nasal Cavity Cancer
Small Cell Cancer of the Lung
Malignant Melanocytic Neoplasm of the Peripheral Nerve Sheath
Penis Sarcoma
Leiomyosarcoma
Cranial Nerve Malignant Neoplasm
Cerebral Neuroblastoma
Dysgerminoma
Vulvar Granular Cell Tumor
Peripheral Nervous System Benign Neoplasm
Autonomic Nervous System Benign Neoplasm
Anal Neuroendocrine Tumor
Lung Cancer
Achalasia
Middle Ear Adenoma
Auditory System Benign Neoplasm
Pheochromocytoma
Bladder Small Cell Carcinoma
Malignant Granular Cell Myoblastoma
Congenital Granular Cell Tumor
Sertoli-Leydig Cell Tumor
Scrapie
Cloacogenic Carcinoma
Sensory Organ Benign Neoplasm
Chondroblastoma
Optic Nerve Astrocytoma
Transitional Cell Carcinoma
Trigeminal Neuralgia
Thymus Small Cell Carcinoma
Askin's Tumor
Hemiplegia
Large Cell Carcinoma with Rhabdoid Phenotype
Germ Cell Cancer
Neuronal Intestinal Dysplasia, Type B
Auditory System Cancer
Neurilemmoma
Meningeal Melanocytoma
Carotid Body Cancer
Benign Teratoma
Breast Neuroendocrine Neoplasm
Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor
Ureter Small Cell Carcinoma
Large Cell Neuroendocrine Carcinoma
Rhabdomyosarcoma 2
Pleurisy
Malignant Teratoma
Cervix Small Cell Carcinoma
Rhabdomyosarcoma
Cerebellar Liponeurocytoma
Carcinoid Syndrome
Cutaneous Ganglioneuroma
Urinary Bladder Small Cell Neuroendocrine Carcinoma
Desmoplastic Small Round Cell Tumor
Sertoli Cell Tumor
Anaplastic Large Cell Lymphoma
Ovarian Large-Cell Neuroendocrine Carcinoma
Microcystic Adenoma
Adrenal Cortical Adenoma
Lung Benign Neoplasm
Conventional Fibrosarcoma
Appendicitis
Coats Disease
Cerebellar Medulloblastoma
Small Cell Carcinoma
Medulloepithelioma
Lung Large Cell Carcinoma
Akinetic Mutism
Sinonasal Undifferentiated Carcinoma
Gallbladder Small Cell Carcinoma
Central Neurocytoma
Tubular Adenocarcinoma
Ewing Sarcoma of Bone
Paraneoplastic Cerebellar Degeneration
Hemangioma
Lung Oat Cell Carcinoma
Mediastinal Cancer
Pleomorphic Adenoma
Retinoblastoma
Pericarditis
Pineocytoma
Central Nervous System Embryonal Tumor
Tuberous Sclerosis
Sarcoma
Central Nervous System Melanocytic Neoplasm
Angiomyoma
Medulloblastoma
Ovarian Small Cell Carcinoma
Horner's Syndrome
Prostate Small Cell Carcinoma
Plexiform Schwannoma
Pineal Gland Cancer
Intracranial Primitive Neuroectodermal Tumor
Parachordoma
Dysentery
Adrenal Neuroblastoma
Paranasal Sinus Cancer
Extraosseous Ewing Sarcoma
Vaginal Glandular Tumor
Asphyxia Neonatorum
Carcinosarcoma
Cerebellum Cancer
Cerebrovascular Benign Neoplasm
Papillary Ependymoma
Meningitis
Hydrocephalus
Jejunal Neoplasm
Squamous Cell Carcinoma
Lymphoblastic Lymphoma
Cerebral Primitive Neuroectodermal Tumor
Pancreatoblastoma
Differentiating Neuroblastoma
Colon Neuroendocrine Neoplasm
Cerebellopontine Angle Primitive Neuroectodermal Tumor
Granular Cell Tumor of the Sellar Region
Ampulla of Vater Benign Neoplasm
Adrenal Carcinoma
Mixed Ductal-Endocrine Carcinoma
Supratentorial Cancer
Ectomesenchymoma
Central Nervous System Mesenchymal Non-Meningothelial Tumor
Lung Disease
Prostate Cancer
Orbital Cancer
Neurofibromatosis, Type I
Cerebrum Cancer
Gastrointestinal Neuroendocrine Tumor
Gliosarcoma
Atypical Follicular Adenoma
Cystic Teratoma
Extraskeletal Mesenchymal Chondrosarcoma
Blastoma
Stroke, Ischemic
Pulmonary Large Cell Neuroendocrine Carcinoma
Amelanotic Melanoma
Papilloma of Choroid Plexus
Islet Cell Tumor
Chondrosarcoma, Extraskeletal Myxoid
Intracranial Embolism
Mature Teratoma of the Ovary
Malignant Triton Tumor
Pineoblastoma
Inappropriate Adh Syndrome
Mature Teratoma
Pulmonary Neuroendocrine Tumor
Supratentorial Primitive Neuroectodermal Tumor
Basaloid Squamous Cell Carcinoma
Endocrine Pancreas Disease
Epithelioid Malignant Peripheral Nerve Sheath Tumor
Pineal Region Teratoma
Obstructive Hydrocephalus
Breast Granular Cell Tumor
Brain Cancer
Perivascular Tumor
Adrenal Medulla Cancer
Nodular Ganglioneuroblastoma
Malignant Pheochromocytoma
Neurofibrosarcoma
Skin Benign Neoplasm
Prostate Neuroendocrine Neoplasm
Spinal Cancer
Cutaneous Fibrous Histiocytoma
Parietal Lobe Neoplasm
Basal Cell Carcinoma
Lymphoepithelioma-Like Carcinoma
Gangliocytoma
Small Intestine Benign Neoplasm
Partial Cryptophthalmia
Cerebral Ventricle Cancer
Vulvar Apocrine Adenocarcinoma
Skeletal Muscle Cancer
Pacinian Tumor
Hemangiopericytoma, Malignant
Meningothelial Meningioma
Neuroblastoma
Connective Tissue Benign Neoplasm
Muscle Cancer
Peripheral Nervous System Neoplasm
Heart Disease
Mixed Germ Cell Cancer
Frontal Lobe Neoplasm
Bladder Lateral Wall Cancer
Breast Leiomyosarcoma
Mixed Cell Type Cancer
Tetralogy of Fallot
Bile Duct Mucinous Adenocarcinoma
Intracranial Hypertension
Lipoma of Spermatic Cord
Paratesticular Lipoma
Pineal Region Choriocarcinoma
Spinal Cord Oligodendroglioma
Autonomic Nervous System Neoplasm
Endocrine Organ Benign Neoplasm
Nasal Cavity Olfactory Neuroblastoma
Central Nervous System Benign Neoplasm
Intracranial Berry Aneurysm
Gastric Body Carcinoma
Thyroid Gland Medullary Carcinoma
Cardiovascular Organ Benign Neoplasm
Lung Combined Large Cell Neuroendocrine Carcinoma
Laryngeal Neuroendocrine Tumor
Renal Cell Carcinoma, Nonpapillary
Appendix Carcinoid Tumor
Suppression of Tumorigenicity 12
Colorectal Cancer
Skin Granular Cell Tumor
Paranasal Sinus Lymphoma
Endobronchial Leiomyoma
Spinocerebellar Ataxia 45
Embryonal Rhabdomyosarcoma
Cystic Basal Cell Carcinoma
Von Hippel-Lindau Syndrome
Peripheral Nervous System Disease
Hypermethioninemia Due to Adenosine Kinase Deficiency
Bone Osteosarcoma
Wilms Tumor 1
Meningioma, Familial
Hirschsprung Disease 1
Nervous System Disease
