智鼠故事 
Kit-LSL-T2A-DTR-P2A-Dre
复苏/繁育服务
产品名称：
Kit-LSL-T2A-DTR-P2A-Dre
产品编号：
I001102
品系背景：
C57BL/6JCya
表达组织/细胞举例：
肺内皮细胞、骨髓肥大细胞等
* 使用本品系发表的文献需注明：Kit-LSL-T2A-DTR-P2A-Dre mice (Catalog I001102) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
只
品系描述
小鼠Kit基因的TGA终止密码子被"loxP-6*SV40 pA-loxP-T2A-DTR-P2A- Dre"取代。当该品系与Cre工具鼠杂交后，子代小鼠中6*SV40 pA序列被删除并将在肺内皮细胞、骨髓肥大细胞等表达DTR（白喉毒素受体）和Dre。
相关疾病：
Piebald Trait
Gastrointestinal Stromal Tumor
Mastocytosis, Cutaneous
Testicular Germ Cell Cancer
Testicular Germ Cell Tumor
Mastocytosis
Thymoma
B-Lymphoblastic Leukemia/lymphoma with T
Leukemia, Acute Myeloid
Cutaneous Mastocytoma
Testicular Seminomatous Germ Cell Tumor
Acute Mast Cell Leukemia
Chronic Mast Cell Leukemia
Plaque-Form Urticaria Pigmentosa
Typical Urticaria Pigmentosa
Isolated Bone Marrow Mastocytosis
Smoldering Systemic Mastocytosis
Nodular Urticaria Pigmentosa
Bullous Diffuse Cutaneous Mastocytosis
Pseudoxanthomatous Diffuse Cutaneous Mastocytosis
Telangiectasia Macularis Eruptiva Perstans
Systemic Mastocytosis with Associated Hematologic Neoplasm
Melanoma
Acute Myeloblastic Leukemia with Maturation
Lip and Oral Cavity Cancer
Mast-Cell Leukemia
Systemic Mastocytosis
Myeloproliferative Neoplasm
Hematologic Cancer
Acute Myeloid Leukemia with Abnormal Bone Marrow Eosinophils Inv(16)(p13q22) or T(16;16)(p13;q22)
Acute Myeloid Leukemia with T(8;21)(q22;q22) Translocation
Skin Melanoma
Gastric Adenocarcinoma
Ovarian Cancer
