智鼠故事 
Cd2-P2A-CreERT2
复苏/繁育服务
产品名称：
Cd2-P2A-CreERT2
产品编号：
I001170
品系背景：
C57BL/6JCya
表达组织/细胞举例：
T细胞、B细胞
* 使用本品系发表的文献需注明：Cd2-P2A-CreERT2 mice (Catalog I001170) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
只
品系描述
通过基因编辑技术将P2A-CreERT2-WPRE-BGHpA基因表达元件整合到小鼠内源Cd2基因的终止密码子（TAA）处，即在小鼠Cd2基因调控元件的驱动下表达CreERT2重组酶。当该品系与含有loxP位点的小鼠杂交产生的子代小鼠经他莫昔芬诱导后，预计将在T细胞和B细胞中发生由Cre重组酶介导的loxP位点间的序列重组。
相关疾病：
Mastocytosis, Cutaneous
Lethal Midline Granuloma
Extracutaneous Mastocytoma
Mastocytosis
Aggressive Nk-Cell Leukemia
Sm-Ahnmd
Indolent Systemic Mastocytosis
Hepatosplenic T-Cell Lymphoma
Thymoma
Mixed Phenotype Acute Leukemia, T/myeloid
Lobomycosis
Mast-Cell Sarcoma
Mature T-Cell and Nk-Cell Lymphoma
Follicular Mucinosis
Solitary Mastocytoma of the Skin
Primary Cutaneous Gamma-Delta T-Cell Lymphoma
Aggressive Systemic Mastocytosis
T-Cell Adult Acute Lymphocytic Leukemia
Inflammatory Bowel Disease 4
Nasal Type Extranodal Nk/t-Cell Lymphoma
Inflammatory Bowel Disease 16
T-Cell Prolymphocytic Leukemia
Systemic Epstein-Barr Virus Positive T-Cell Lymphoma of Childhood
Parapsoriasis
Mast-Cell Leukemia
Corneal Dystrophy, Posterior Polymorphous, 2
Adult T-Cell Leukemia/lymphoma
Blastic Plasmacytoid Dendritic Cell Neoplasm
Breast Implant-Associated Anaplastic Large Cell Lymphoma
Systemic Mastocytosis
T-Cell Large Granular Lymphocyte Leukemia
Chronic Nk-Cell Lymphocytosis
Angioimmunoblastic T-Cell Lymphoma
Mast Cell Neoplasm
Acute Biphenotypic Leukemia
Adult Acute Lymphocytic Leukemia
Malaria
Peripheral T-Cell Lymphoma
Sezary's Disease
Multiple Sclerosis
Solid Adenocarcinoma with Mucin Production
Benign Mastocytoma
Pancytopenia
Isolated Growth Hormone Deficiency Type Iii
Immune Deficiency Disease
T-Cell Acute Lymphoblastic Leukemia
Diffuse Large B-Cell Lymphoma
Leukemia, Acute Lymphoblastic
Leukemia, Acute Myeloid
Acute Promyelocytic Leukemia
Leukemia, Chronic Lymphocytic
